For over 30 years SAM-e, (short for S-Adenosylmethionine) has been used successfully in Europe to improve mood, joint health, and much more. Now it is gaining popularity in the U.S. for a wide variety of needed benefits.
Study Finds SAM-e Better Than Drugs For Depression
A study released by the U.S. Dept. of Health & Human Services concluded that natural S-adenosylmethionine (SAM-e) is as effective as prescription antidepressants for supporting the body during mild depression.
Compared to placebo, SAM-e showed an improvement of approximately six points (clinically significant) on the Hamilton Rating Scale of Depression after three weeks of supplementation. SAM-e is not associated with the negative side effects of prescription drugs, so it makes a better, more natural choice.
SAM-e was also found to out-perform placebo significantly in decreasing the pain associated with osteoarthritis. Compared to typical medical treatments (NSAIDS) for this condition, SAM-e performed quite favorably. Nature’s Sunshine offers only natural SAM-e, not the synthetic forms some other manufacturers offer. Natural SAM-e is better utilized by the body.
SAM-e is a natural compound manufactured by the body to help with a variety of functions, including mood regulation, cognitive function, general nerve and inflammatory conditions, and liver and heart health. Most of the body’s SAM-e is made in the liver.
Unfortunately stress, low dietary standards and aging can diminish available SAM-e, thereby generating structural, mental and emotional consequences.
People who are deficient in this nutrient, or who cannot tolerate antidepressant drugs or anti-inflammatory agents might benefit from supplemental SAM-e.
• Enhances mood – used in manufacturing neurotransmitters (like serotonin), phospholipids and hormones (like adrenaline and melatonin).
• Supports joints – involved in the production of various cartilage components.
• Arterial/heart health – helps in the production of glutathione, a powerful antioxidant.
• Promotes longevity by aiding the regeneration of new cells.
• Facilitates muscle/nerve harmony – supports structural system health.
• Supports liver health and repair.
Nature’s Sunshine Advantage
Experts warn consumers to purchase SAM-e only from reputable manufacturers. Nature’s Sunshine makes sure you get the quality you deserve at an affordable price.
Each tablet of Nature’s Sunshine SAM-e is enterically coated so SAM-e is only released in the small intestine for maximum absorption.
How it Works
SAM-e is naturally present in all living cells and is required in over 40 biochemical reactions. It is necessary for manufacturing important brain compounds like neurotransmitters and phospholipids. It is also involved with the production of hormones (like serotonin and melatonin), proteins, the powerful antioxidant glutathione and various cartilage components. It also appears to help fight aging by regenerating new cells, especially in joint and liver tissue.
It is important for consumers to know that stabilizing compounds can weigh as much as the SAM-e molecule. Consequently, a tablet containing 200 mg of S-adenosyl-methionine tosylate will contain only 100 mg of SAM-e. Not all labels, make this clear.
For example, while a product’s label claims 200 mg of SAM-e per tablet, this weight actually may include the weight of the stabilizing compound, so a person using the product would only get about 100 mg of actual SAM-e from each tablet. Nature’s Sunshine tells you the truth. The 400 mg tablet provides 200 mg of available SAM-e.
Take 2 tablets once or twice daily on an empty stomach with 8 oz. of pure water. For best results, add one capsule of Nature’s Sunshine B-Complex vitamins each time you take SAM-e. Some people cannot take B vitamins on an empty stomach, so you could take it with the following meal is used.
Generally recommended daily doses of SAMe can range from 200 to 800 mg, depending upon the condition, severity, and course of treatment. It is often recommended that one start with a dose of only 200 mg or 400 mg of SAMe for the first day of therapy and increase thereafter. These daily amounts should not be taken at once but in divided doses, such as 200 mg twice a day in the case of a 400 mg total daily dose, or 200 mg four times a day in the case of an 800 mg total daily dose. Noticeable improvements when taking SAMe can take from a few days to four or five weeks.
“My husband has always had a unique metabolism, and sometimes this affects his moods. I gave him a bottle of Nature’s Sunshine’s SAM-e, and an hour after taking his very first capsules, he started feeling the effects. His energy level rose right away and he was feeling better in no time. I could hardly believe it. When the bottle was empty, he asked for more and got after me because we were out. I guess it’s time to order more SAM-e!” L.Clark
“I have a friend who suffers from arthritis. I thought SAM-e might help with her condition, so I gave her a bottle. The results were wonderful- but they weren’t what I had expected. She said the SAM-e calmed her nerves and gave her a really positive feeling. She’s nervous in the first place, and being an executive at a bank doesn’t help her state of mind. But she reported back to me that SAM-e took the edge right off. Now she’s asking for more. It’s wonderful!” Margarite
“I love the Nature’s Sunshine SAM-e. It’s the best! Other products I’ve tried have tended to make me feel jittery and unsure. This SAM-e has gotten me feeling better FAST. I highly recommend it.” Kirstin
“My job requires that I bend my knees a lot. When I took Nature’s Sunshine’s SAM-e I felt that my discomfort reduced enormously.” Lillian
“I experienced a real lift with Nature’s Sunshine’s SAM-e. I had started to spiral downward mentally, and in four days the SAM-e pulled me out of it. I was also experiencing difficulty sleeping at night. I often got only four hours of sleep. After being on SAM-e for two weeks, I could sleep from 11 PM to 8 AM. My body was able to catch up on the sleep it had missed. Now I get a restful sleep each night. I’m not going to stop taking this stuff.” Tom M.
These products are not likely to be helpful in severe osteoarthritis when bones already rub bones. A reduction in weight for overweight individuals and switching to low-impact rather than high-impact sports are also recommended for people with osteoarthritis.
If you are taking prescription antidepressants, experiencing anxiety or have bipolar (manic) depression, consult your physician before or during the use of this product. Pregnant or lactating women should consult their healthcare provider prior to taking this supplement. Please consult your physician if gastro intestinal symptoms should occur or increase.